| TM | QB | RTG | TD | INT | SKD | POS | GP | CMP | ATT | CMP% | YDS | AVG | YDS/G | LNG | TD | INT | SACK | SYL | QBR | RTG | ||
| ARI | ARI | BRISSETT | 97 | 66.8 | 1.4 | 0.4 | 3.0 | QB | 8 | 175 | 262 | 66.8 | 1887 | 7.2 | 235.9 | 50 | 11 | 3 | 24 | 187 | 40 | 97 |
| ATL | ATL | * COUSINS | 83.7 | 64 | 0.5 | 0.3 | 1.0 | QB | 4 | 48 | 75 | 64 | 449 | 6 | 112.3 | 49 | 2 | 1 | 4 | 23 | 33.8 | 83.7 |
| BAL | BAL | JACKSON | 111 | 66.7 | 1.9 | 0.4 | 3.0 | QB | 8 | 130 | 195 | 66.7 | 1595 | 8.2 | 199.4 | 45 | 15 | 3 | 24 | 162 | 63.2 | 111 |
| BUF | BUF | ALLEN | 101.6 | 69.7 | 1.6 | 0.8 | 2.5 | QB | 11 | 228 | 327 | 69.7 | 2709 | 8.3 | 246.3 | 54 | 18 | 9 | 28 | 182 | 58.1 | 101.6 |
| CAR | CAR | YOUNG | 83.8 | 62.7 | 1.4 | 0.8 | 1.8 | QB | 11 | 215 | 343 | 62.7 | 2131 | 6.2 | 193.7 | 54 | 15 | 9 | 20 | 150 | 42.8 | 83.8 |
| CHI | CHI | WILLIAMS | 91.3 | 59.2 | 1.5 | 0.4 | 1.5 | QB | 11 | 213 | 360 | 59.2 | 2,568 | 7.1 | 233.5 | 65 | 16 | 4 | 17 | 116 | 55.3 | 91.3 |
| CIN | CIN | * BURROW | 91.1 | 58.3 | 1.0 | 0.0 | 2.5 | QB | 2 | 21 | 36 | 58.3 | 189 | 5.3 | 94.5 | 25 | 2 | 0 | 5 | 26 | 61.3 | 91.1 |
| CLE | CLE | SANDERS | 13.5 | 25 | 0.0 | 1.0 | 2.0 | QB | 2 | 15 | 36 | 41.7 | 256 | 7.1 | 128 | 66 | 1 | 2 | 3 | 30 | 4.5 | 52.5 |
| DAL | DAL | PRESCOTT | 102.6 | 69.3 | 2.1 | 0.6 | 1.5 | QB | 11 | 276 | 398 | 69.3 | 2941 | 7.4 | 267.4 | 74 | 23 | 7 | 17 | 105 | 74 | 102.6 |
| DEN | DEN | NIX | 86.1 | 61.2 | 1.6 | 0.7 | 1.1 | QB | 11 | 237 | 387 | 61.2 | 2421 | 6.3 | 220.1 | 52 | 18 | 8 | 12 | 73 | 53.5 | 86.1 |
| DET | DET | GOFF | 108.5 | 69.3 | 2.1 | 0.5 | 2.1 | QB | 11 | 244 | 352 | 69.3 | 2769 | 7.9 | 251.7 | 64 | 23 | 5 | 23 | 147 | 54.8 | 108.5 |
| GB | GB | LOVE | 102 | 67.7 | 1.4 | 0.3 | 1.5 | QB | 11 | 224 | 331 | 67.7 | 2560 | 7.7 | 232.7 | 59 | 15 | 3 | 17 | 126 | 70 | 102 |
| HOU | HOU | * STROUD | 93.4 | 66.5 | 1.4 | 0.6 | 2.1 | QB | 8 | 161 | 242 | 66.5 | 1702 | 7 | 212.8 | 50 | 11 | 5 | 17 | 148 | 65.6 | 93.4 |
| IND | IND | JONES (L) | 101.4 | 69.1 | 1.5 | 0.6 | 1.9 | QB | 11 | 242 | 350 | 69.1 | 2840 | 8.1 | 258.2 | 75 | 17 | 7 | 21 | 152 | 65.9 | 101.4 |
| JAC | JAX | LAWRENCE | 79.4 | 59.8 | 1.3 | 1.0 | 2.6 | QB | 11 | 220 | 368 | 59.8 | 2407 | 6.5 | 218.8 | 46 | 14 | 11 | 29 | 176 | 42.9 | 79.4 |
| KC | KC | MAHOMES | 93.8 | 64.4 | 1.6 | 0.6 | 2.2 | QB | 11 | 262 | 407 | 64.4 | 2977 | 7.3 | 270.6 | 61 | 18 | 7 | 24 | 142 | 71.9 | 93.8 |
| LAC | LAC | HERBERT | 94.2 | 66.5 | 1.7 | 0.8 | 3.2 | QB | 11 | 250 | 376 | 66.5 | 2691 | 7.2 | 244.6 | 60 | 19 | 9 | 35 | 213 | 60.4 | 94.2 |
| LAR | LAR | STAFFORD | 113.7 | 66.5 | 2.7 | 0.2 | 1.4 | QB | 11 | 248 | 373 | 66.5 | 2830 | 7.6 | 257.3 | 88 | 30 | 2 | 15 | 98 | 69.7 | 113.7 |
| LVR | LV | SMITH | 82.4 | 66.6 | 1.2 | 1.2 | 3.7 | QB | 11 | 235 | 353 | 66.6 | 2367 | 6.7 | 215.2 | 61 | 13 | 13 | 41 | 291 | 29.3 | 82.4 |
| MIA | MIA | TAGOVAILOA | 88.1 | 68.3 | 1.5 | 1.2 | 1.9 | QB | 11 | 213 | 312 | 68.3 | 2123 | 6.8 | 193 | 47 | 17 | 13 | 21 | 133 | 43.5 | 88.1 |
| MIN | MIN | * JMAC (L) | 57.9 | 54.1 | 1.0 | 1.7 | 3.3 | QB | 6 | 86 | 159 | 54.1 | 929 | 5.8 | 154.8 | 62 | 6 | 10 | 20 | 112 | 24.8 | 57.9 |
| NE | NE | MAYE | 110.7 | 71 | 1.8 | 0.5 | 3.1 | QB | 12 | 252 | 355 | 71 | 3130 | 8.8 | 260.8 | 72 | 21 | 6 | 37 | 172 | 72.7 | 110.7 |
| NOS | NO | SHOUGH | 81.1 | 64.3 | 0.6 | 0.6 | 2.0 | QB | 5 | 81 | 126 | 64.3 | 829 | 6.6 | 165.8 | 62 | 3 | 3 | 10 | 72 | 41.3 | 81.1 |
| NYG | NYG | WINSTON | 83.3 | 56.9 | 1.0 | 1.0 | 1.5 | QB | 2 | 37 | 65 | 56.9 | 567 | 8.7 | 283.5 | 42 | 2 | 2 | 3 | 11 | 74.4 | 83.3 |
| NYJ | NYJ | TAYLOR | 76 | 61.9 | 1.0 | 1.0 | 3.0 | QB | 4 | 60 | 97 | 61.9 | 601 | 6.2 | 150.3 | 40 | 4 | 4 | 12 | 69 | 46.5 | 76 |
| PHI | PHI | HURTS | 106 | 67.2 | 1.5 | 0.1 | 2.5 | QB | 11 | 207 | 308 | 67.2 | 2284 | 7.4 | 207.6 | 79 | 17 | 1 | 27 | 159 | 58.8 | 106 |
| PIT | PIT | RODGERS | 97.7 | 66.4 | 1.9 | 0.7 | 1.9 | QB | 10 | 192 | 289 | 66.4 | 1969 | 6.8 | 196.9 | 80 | 19 | 7 | 19 | 121 | 43.8 | 97.7 |
| SAN | SAN | PURDY | 88.6 | 68.7 | 2.0 | 1.8 | 0.8 | QB | 4 | 90 | 131 | 68.7 | 979 | 7.5 | 244.8 | 45 | 8 | 7 | 3 | 29 | 65.3 | 88.6 |
| SEA | SEA | DARNOLD | 106.2 | 69.5 | 1.7 | 0.9 | 1.0 | QB | 11 | 207 | 298 | 69.5 | 2785 | 9.3 | 253.2 | 67 | 19 | 10 | 11 | 67 | 69.2 | 106.2 |
| TB | TB | * MAYFIELD (Q) | 93.1 | 62.7 | 1.6 | 0.5 | 2.0 | QB | 11 | 225 | 359 | 62.7 | 2406 | 6.7 | 218.7 | 77 | 18 | 5 | 22 | 155 | 60.9 | 93.1 |
| TEN | TEN | WARD | 75.7 | 59.4 | 0.6 | 0.5 | 4.1 | QB | 11 | 222 | 374 | 59.4 | 2210 | 5.9 | 200.9 | 47 | 7 | 6 | 45 | 342 | 33.2 | 75.7 |
| WAS | WSH | MARIOTA | 90.3 | 65.7 | 1.0 | 0.7 | 1.4 | QB | 7 | 92 | 140 | 65.7 | 1065 | 7.6 | 152.1 | 56 | 7 | 5 | 10 | 63 | 58.8 | 90.3 |