| TM | QB | RTG | TD | INT | SKD | POS | GP | CMP | ATT | CMP% | YDS | AVG | YDS/G | LNG | TD | INT | SACK | SYL | QBR | RTG | ||
| ARI | BRISSETT | 95.7 | 66.3 | 1.6 | 0.5 | 2.8 | QB | 11 | 256 | 386 | 66.3 | 2708 | 7 | 246.2 | 50 | 18 | 6 | 31 | 219 | 44.3 | 95.7 | |
| ATL | COUSINS | 86.3 | 62.6 | 0.9 | 0.4 | 1.1 | QB | 7 | 114 | 182 | 62.6 | 1218 | 6.7 | 174 | 49 | 6 | 3 | 8 | 51 | 40.8 | 86.3 | |
| BAL | JACKSON (P) | 101.4 | 63.5 | 1.6 | 0.5 | 3.0 | QB | 11 | 174 | 274 | 63.5 | 2210 | 8.1 | 200.9 | 45 | 18 | 6 | 33 | 223 | 60.1 | 101.4 | |
| BUF | ALLEN | 104.3 | 70 | 1.8 | 0.7 | 2.4 | QB | 14 | 284 | 406 | 70 | 3276 | 8.1 | 234 | 54 | 25 | 10 | 33 | 212 | 66.4 | 104.3 | |
| CAR | YOUNG | 88.4 | 63.3 | 1.5 | 0.7 | 1.8 | QB | 13 | 245 | 387 | 63.3 | 2500 | 6.5 | 192.3 | 54 | 19 | 9 | 23 | 171 | 47.6 | 88.4 | |
| CHI | WILLIAMS | 88.8 | 58 | 1.5 | 0.4 | 1.6 | QB | 14 | 266 | 459 | 58 | 3,150 | 6.9 | 225 | 65 | 21 | 6 | 23 | 158 | 54.3 | 88.8 | |
| CIN | BURROW | 84.3 | 60.5 | 1.6 | 0.8 | 2.0 | QB | 5 | 95 | 157 | 60.5 | 959 | 6.1 | 191.8 | 43 | 8 | 4 | 10 | 68 | 56.5 | 84.3 | |
| CLE | SANDERS | 13.5 | 25 | 0.0 | 1.0 | 2.0 | QB | 5 | 72 | 138 | 52.2 | 946 | 6.9 | 189.2 | 66 | 5 | 6 | 13 | 112 | 16.9 | 68.1 | |
| DAL | PRESCOTT | 99.1 | 68.4 | 1.9 | 0.7 | 1.7 | QB | 14 | 357 | 522 | 68.4 | 3931 | 7.5 | 280.8 | 74 | 26 | 10 | 24 | 164 | 72.8 | 99.1 | |
| DEN | NIX | 89.7 | 63.5 | 1.6 | 0.6 | 1.1 | QB | 14 | 320 | 504 | 63.5 | 3256 | 6.5 | 232.6 | 52 | 23 | 9 | 16 | 87 | 59.1 | 89.7 | |
| DET | GOFF | 110.4 | 69.3 | 2.1 | 0.4 | 2.0 | QB | 14 | 314 | 453 | 69.3 | 3672 | 8.1 | 262.3 | 64 | 29 | 5 | 28 | 192 | 60.6 | 110.4 | |
| GB | LOVE | 101.9 | 66.4 | 1.6 | 0.4 | 1.5 | QB | 14 | 283 | 426 | 66.4 | 3304 | 7.8 | 236 | 59 | 23 | 6 | 21 | 169 | 73.8 | 101.9 | |
| HOU | STROUD | 94.1 | 65.3 | 1.4 | 0.5 | 2.1 | QB | 11 | 220 | 337 | 65.3 | 2441 | 7.2 | 221.9 | 57 | 15 | 6 | 23 | 189 | 62.5 | 94.1 | |
| IND | RIVERS | 73.1 | 66.7 | 1.0 | 1.0 | 1.0 | QB | 1 | 18 | 27 | 66.7 | 120 | 4.4 | 120 | 17 | 1 | 1 | 1 | 2 | 52.3 | 73.1 | |
| JAC | LAWRENCE | 87.9 | 59.7 | 1.6 | 0.8 | 2.3 | QB | 14 | 273 | 457 | 59.7 | 3210 | 7 | 229.3 | 50 | 23 | 11 | 32 | 203 | 51.8 | 87.9 | |
| KC | * MENSHEW | 30.8 | 60 | 0.0 | 0.3 | 0.0 | QB | 3 | 3 | 5 | 60 | 22 | 4.4 | 7.3 | 11 | 0 | 1 | 0 | 0 | 27.4 | 30.8 | |
| LAC | HERBERT | 92.2 | 65.6 | 1.6 | 0.9 | 3.5 | QB | 14 | 296 | 451 | 65.6 | 3191 | 7.1 | 227.9 | 60 | 23 | 12 | 49 | 266 | 58.2 | 92.2 | |
| LAR | STAFFORD | 112.2 | 66.4 | 2.6 | 0.4 | 1.4 | QB | 14 | 312 | 470 | 66.4 | 3722 | 7.9 | 265.9 | 88 | 37 | 5 | 19 | 122 | 69.7 | 112.2 | |
| LV | * SMITH | 84.5 | 67 | 1.2 | 1.1 | 3.8 | QB | 13 | 266 | 397 | 67 | 2648 | 6.7 | 203.7 | 61 | 16 | 14 | 49 | 350 | 32.4 | 84.5 | |
| MIA | * EWERS | 81.8 | 62.5 | 0.0 | 0.0 | 2.0 | QB | 1 | 5 | 8 | 62.5 | 53 | 6.6 | 53 | 40 | 0 | 0 | 2 | 20 | 25.5 | 81.8 | |
| MIN | JMAC | 72.1 | 56.8 | 1.4 | 1.4 | 3.0 | QB | 8 | 117 | 206 | 56.8 | 1342 | 6.5 | 167.8 | 62 | 11 | 11 | 24 | 124 | 34.7 | 72.1 | |
| NE | MAYE | 109.1 | 70.9 | 1.6 | 0.5 | 3.1 | QB | 14 | 290 | 409 | 70.9 | 3567 | 8.7 | 254.8 | 72 | 23 | 7 | 43 | 194 | 71.2 | 109.1 | |
| NO | SHOUGH | 85.9 | 66.7 | 0.8 | 0.6 | 2.8 | QB | 8 | 144 | 216 | 66.7 | 1484 | 6.9 | 185.5 | 62 | 6 | 5 | 22 | 137 | 46.3 | 85.9 | |
| NYG | DART | 92.7 | 62.5 | 1.2 | 0.4 | 2.2 | QB | 11 | 165 | 264 | 62.5 | 1802 | 6.8 | 163.8 | 44 | 13 | 4 | 24 | 102 | 61.8 | 92.7 | |
| NYJ | * COOK | 44.3 | 57.1 | 0.5 | 2.5 | 4.5 | QB | 2 | 36 | 63 | 57.1 | 339 | 5.4 | 169.5 | 25 | 1 | 5 | 9 | 49 | 19.1 | 44.3 | |
| PHI | HURTS | 99.4 | 65.2 | 1.6 | 0.4 | 2.1 | QB | 14 | 259 | 397 | 65.2 | 2929 | 7.4 | 209.2 | 79 | 22 | 6 | 29 | 172 | 54.6 | 99.4 | |
| PIT | RODGERS | 98.8 | 66.8 | 1.7 | 0.5 | 1.8 | QB | 13 | 248 | 371 | 66.8 | 2594 | 7 | 199.5 | 80 | 22 | 7 | 23 | 153 | 43.3 | 98.8 | |
| SAN | PURDY | 96 | 67.9 | 2.0 | 1.2 | 1.0 | QB | 6 | 129 | 190 | 67.9 | 1442 | 7.6 | 240.3 | 45 | 12 | 7 | 6 | 39 | 72.9 | 96 | |
| SEA | DARNOLD | 102 | 67.4 | 1.6 | 0.8 | 1.3 | QB | 14 | 263 | 390 | 67.4 | 3433 | 8.8 | 245.2 | 67 | 22 | 11 | 18 | 121 | 62.5 | 102 | |
| TB | MAYFIELD | 90.6 | 61.2 | 1.6 | 0.5 | 2.1 | QB | 14 | 276 | 451 | 61.2 | 2999 | 6.7 | 214.2 | 77 | 22 | 7 | 29 | 192 | 59 | 90.6 | |
| TEN | WARD | 76.5 | 59.3 | 0.8 | 0.5 | 3.5 | QB | 14 | 278 | 469 | 59.3 | 2638 | 5.6 | 188.4 | 47 | 11 | 7 | 49 | 371 | 31.2 | 76.5 | |
| WSH | MARIOTA | 87 | 62 | 1.0 | 0.7 | 1.5 | QB | 10 | 132 | 213 | 62 | 1600 | 7.5 | 160 | 56 | 10 | 7 | 15 | 105 | 51.8 | 87 | |