| TM | QB | RTG | TD | INT | SKD | POS | GP | CMP | ATT | CMP% | YDS | AVG | YDS/G | LNG | TD | INT | SACK | SYL | QBR | RTG | ||
| ARI | BRISSETT | 93.5 | 64.5 | 1.6 | 0.5 | 2.8 | QB | 13 | 293 | 454 | 64.5 | 3123 | 6.9 | 240.2 | 50 | 21 | 7 | 37 | 255 | 41.3 | 93.5 | |
| ATL | COUSINS | 86.8 | 62.4 | 1.0 | 0.4 | 1.0 | QB | 9 | 148 | 237 | 62.4 | 1541 | 6.5 | 171.2 | 49 | 9 | 4 | 9 | 58 | 52.2 | 86.8 | |
| BAL | * JACKSON | 101.4 | 63.7 | 1.5 | 0.5 | 2.8 | QB | 12 | 181 | 284 | 63.7 | 2311 | 8.1 | 192.6 | 45 | 18 | 6 | 33 | 223 | 63.3 | 101.4 | |
| BUF | ALLEN | 102.2 | 69.3 | 1.6 | 0.6 | 2.5 | QB | 16 | 319 | 460 | 69.3 | 3668 | 8 | 229.3 | 54 | 25 | 10 | 40 | 298 | 65.1 | 102.2 | |
| CAR | YOUNG | 87 | 63.2 | 1.4 | 0.7 | 1.8 | QB | 15 | 280 | 443 | 63.2 | 2745 | 6.2 | 183 | 54 | 21 | 10 | 27 | 202 | 48 | 87 | |
| CHI | WILLIAMS | 90.3 | 57.9 | 1.6 | 0.4 | 1.4 | QB | 16 | 310 | 535 | 57.9 | 3,730 | 7 | 233.1 | 65 | 25 | 6 | 23 | 158 | 58.1 | 90.3 | |
| CIN | BURROW | 100.1 | 65.5 | 2.0 | 0.6 | 2.1 | QB | 7 | 144 | 220 | 65.5 | 1573 | 7.2 | 224.7 | 43 | 14 | 4 | 15 | 99 | 63.2 | 100.1 | |
| CLE | SANDERS | 13.5 | 25 | 0.0 | 1.0 | 2.0 | QB | 7 | 109 | 190 | 57.4 | 1289 | 6.8 | 184.1 | 66 | 7 | 10 | 17 | 135 | 20.2 | 68.5 | |
| DAL | PRESCOTT | 99.9 | 67.4 | 1.9 | 0.6 | 1.9 | QB | 16 | 397 | 589 | 67.4 | 4482 | 7.6 | 280.1 | 86 | 30 | 10 | 31 | 208 | 71.9 | 99.9 | |
| DEN | NIX | 88.2 | 63.5 | 1.6 | 0.7 | 1.1 | QB | 16 | 374 | 589 | 63.5 | 3790 | 6.4 | 236.9 | 52 | 25 | 11 | 18 | 102 | 58.3 | 88.2 | |
| DET | GOFF | 107 | 68.3 | 2.1 | 0.4 | 2.3 | QB | 16 | 366 | 536 | 68.3 | 4233 | 7.9 | 264.6 | 64 | 33 | 7 | 36 | 244 | 57.2 | 107 | |
| GB | * LOVE | 101.2 | 66.3 | 1.5 | 0.4 | 1.4 | QB | 15 | 291 | 439 | 66.3 | 3381 | 7.7 | 225.4 | 59 | 23 | 6 | 21 | 169 | 73.4 | 101.2 | |
| HOU | STROUD | 92.6 | 64.8 | 1.4 | 0.6 | 1.8 | QB | 13 | 259 | 400 | 64.8 | 2872 | 7.2 | 220.9 | 75 | 18 | 8 | 23 | 189 | 61.9 | 92.6 | |
| IND | LEONARD | 40.6 | 54.5 | 0.0 | 0.5 | 0.3 | QB | 4 | 18 | 33 | 54.5 | 145 | 4.4 | 36.3 | 29 | 0 | 2 | 1 | 9 | 49.1 | 40.6 | |
| JAX | LAWRENCE | 88.7 | 60.2 | 1.6 | 0.8 | 2.4 | QB | 16 | 319 | 530 | 60.2 | 3752 | 7.1 | 234.5 | 63 | 26 | 12 | 39 | 231 | 56.6 | 88.7 | |
| KC | * OLADOKIN | 82.9 | 63.2 | 0.5 | 0.0 | 2.5 | QB | 2 | 24 | 38 | 63.2 | 177 | 4.7 | 88.5 | 31 | 1 | 0 | 5 | 53 | 33.8 | 82.9 | |
| LAC | HERBERT | 94.1 | 66.4 | 1.6 | 0.8 | 3.4 | QB | 16 | 340 | 512 | 66.4 | 3727 | 7.3 | 232.9 | 60 | 26 | 13 | 54 | 301 | 60.2 | 94.1 | |
| LAR | STAFFORD | 108.8 | 65.2 | 2.6 | 0.5 | 1.4 | QB | 16 | 363 | 557 | 65.2 | 4448 | 8 | 278 | 88 | 42 | 8 | 22 | 143 | 70.1 | 108.8 | |
| LV | PICKETT | 73.7 | 65.9 | 0.2 | 0.2 | 1.2 | QB | 5 | 27 | 41 | 65.9 | 185 | 4.5 | 37 | 26 | 1 | 1 | 6 | 40 | 6.4 | 73.7 | |
| MIA | EWERS | 87.2 | 65 | 0.7 | 0.7 | 1.3 | QB | 3 | 39 | 60 | 65 | 485 | 8.1 | 161.7 | 63 | 2 | 2 | 4 | 39 | 31.2 | 87.2 | |
| MIN | * JJMAC | 71.2 | 57.3 | 1.2 | 1.3 | 3.0 | QB | 9 | 126 | 220 | 57.3 | 1450 | 6.6 | 161.1 | 62 | 11 | 12 | 27 | 149 | 33.4 | 71.2 | |
| NE | MAYE | 112.9 | 71.7 | 1.9 | 0.5 | 2.9 | QB | 16 | 340 | 474 | 71.7 | 4203 | 8.9 | 262.7 | 72 | 30 | 8 | 47 | 201 | 76.5 | 112.9 | |
| NO | SHOUGH | 92.1 | 67.8 | 0.9 | 0.5 | 2.7 | QB | 10 | 198 | 292 | 67.8 | 2125 | 7.3 | 212.5 | 62 | 9 | 5 | 27 | 168 | 48.3 | 92.1 | |
| NYG | DART | 89.8 | 63.2 | 1.0 | 0.4 | 2.4 | QB | 13 | 194 | 307 | 63.2 | 2042 | 6.7 | 157.1 | 44 | 13 | 5 | 31 | 141 | 58.1 | 89.8 | |
| NYJ | COOK | 52.9 | 58.8 | 0.3 | 1.8 | 4.5 | QB | 4 | 77 | 131 | 58.8 | 679 | 5.2 | 169.8 | 26 | 1 | 7 | 18 | 118 | 10 | 52.9 | |
| PHI | HURTS | 98.5 | 64.8 | 1.6 | 0.4 | 2.0 | QB | 16 | 294 | 454 | 64.8 | 3224 | 7.1 | 201.5 | 79 | 25 | 6 | 32 | 181 | 55.3 | 98.5 | |
| PIT | RODGERS | 95.3 | 65.6 | 1.5 | 0.5 | 1.8 | QB | 15 | 296 | 451 | 65.6 | 3028 | 6.7 | 201.9 | 80 | 23 | 7 | 27 | 176 | 41.9 | 95.3 | |
| SAN | PURDY | 104.2 | 69.3 | 2.5 | 1.1 | 1.0 | QB | 8 | 178 | 257 | 69.3 | 2040 | 7.9 | 255 | 45 | 20 | 9 | 8 | 46 | 77.6 | 104.2 | |
| SEA | DARNOLD | 99.2 | 67.2 | 1.6 | 0.9 | 1.6 | QB | 16 | 303 | 451 | 67.2 | 3850 | 8.5 | 240.6 | 67 | 25 | 14 | 25 | 169 | 58.3 | 99.2 | |
| TB | MAYFIELD | 90.3 | 62.8 | 1.6 | 0.6 | 2.1 | QB | 16 | 327 | 521 | 62.8 | 3490 | 6.7 | 218.1 | 77 | 25 | 10 | 34 | 229 | 60.8 | 90.3 | |
| TEN | WARD | 79.8 | 59.6 | 0.9 | 0.4 | 3.4 | QB | 16 | 320 | 537 | 59.6 | 3117 | 5.8 | 194.8 | 47 | 15 | 7 | 55 | 410 | 32.1 | 79.8 | |
| WSH | * JOHNSON | 72.5 | 62.5 | 0.0 | 0.3 | 0.5 | QB | 4 | 20 | 32 | 62.5 | 241 | 7.5 | 60.3 | 41 | 0 | 1 | 2 | 14 | 15.4 | 72.5 | |