| TM | QB | RTG | TD | INT | SKD | POS | GP | CMP | ATT | CMP% | YDS | AVG | YDS/G | LNG | TD | INT | SACK | SYL | QBR | RTG | |
| 1 | ARI | BYE | 88.6 | 1.2 | 0.2 | 2.6 | QB | 5 | 110 | 161 | 68.3 | 962 | 6 | 192.4 | 45 | 6 | 1 | 13 | 111 | 44.5 | 88.6 |
| 2 | ATL | PENIX ? | 85.2 | 1.3 | 0.5 | 1.7 | QB | 6 | 119 | 195 | 61 | 1409 | 7.2 | 234.8 | 69 | 8 | 3 | 10 | 70 | 48.3 | 85.2 |
| 3 | BAL | HUNTLEY | 76.5 | 14.0 | 1.0 | 17.0 | QB | 1 | 10 | 15 | 66.7 | 68 | 4.5 | 68 | 18 | 14 | 1 | 17 | 23 | 64 | 76.5 |
| 4 | BUF | ALLEN | 103.1 | 2.2 | 0.7 | 2.8 | QB | 6 | 122 | 178 | 68.5 | 1397 | 7.8 | 232.8 | 51 | 13 | 4 | 17 | 65 | 62.6 | 103.1 |
| 5 | CAR | * DALTON | 123.2 | 3.7 | 2.0 | 4.0 | QB | 3 | 9 | 13 | 69.2 | 118 | 9.1 | 39.3 | 33 | 11 | 6 | 12 | 9 | 63.3 | 123.2 |
| 6 | CHI | WILLIAMS | 92.9 | 2.0 | 0.7 | 2.3 | QB | 6 | 113 | 185 | 61.1 | 1351 | 7.3 | 225.2 | 65 | 12 | 4 | 14 | 75 | 52.2 | 92.9 |
| 7 | CIN | FLACCO | 74.8 | 2.2 | 1.3 | 2.7 | QB | 6 | 153 | 252 | 60.7 | 1376 | 5.5 | 229.3 | 37 | 13 | 8 | 16 | 74 | 42.6 | 74.8 |
| 8 | CLE | GABRIEL | 82.5 | 1.0 | 0.4 | 2.2 | QB | 5 | 64 | 107 | 59.8 | 546 | 5.1 | 109.2 | 24 | 5 | 2 | 11 | 60 | 30.4 | 82.5 |
| 9 | DAL | PRESCOTT | 107.6 | 2.4 | 0.9 | 2.1 | QB | 7 | 185 | 259 | 71.4 | 1881 | 7.3 | 268.7 | 74 | 17 | 6 | 15 | 43 | 81.2 | 107.6 |
| 10 | DEN | NIX | 87.3 | 2.4 | 0.9 | 1.3 | QB | 7 | 160 | 256 | 62.5 | 1556 | 6.1 | 222.3 | 52 | 17 | 6 | 9 | 50 | 55.8 | 87.3 |
| 11 | DET | BYE | 116.4 | 2.4 | 0.4 | 2.6 | QB | 7 | 152 | 203 | 74.9 | 1,631 | 8 | 233 | 64 | 17 | 3 | 18 | 69 | 66.6 | 116.4 |
| 12 | GB | LOVE | 108.1 | 2.2 | 0.5 | 1.8 | QB | 6 | 122 | 176 | 69.3 | 1438 | 8.2 | 239.7 | 57 | 13 | 3 | 11 | 83 | 70.3 | 108.1 |
| 13 | HOU | STROUD | 91.1 | 0.0 | 0.0 | 0.3 | QB | 6 | 125 | 193 | 64.8 | 1305 | 6.8 | 217.5 | 50 | 0 | 0 | 2 | 139 | 55.3 | 91.1 |
| 14 | IND | JONES | 105.9 | 2.0 | 0.9 | 2.0 | QB | 7 | 152 | 214 | 71 | 1,790 | 8.4 | 255.7 | 75 | 14 | 6 | 14 | 48 | 80.2 | 105.9 |
| 15 | JAC | BYE | 80.6 | 1.3 | 0.9 | 3.0 | QB | 7 | 152 | 259 | 58.7 | 1620 | 6.3 | 231.4 | 46 | 9 | 6 | 21 | 114 | 42.7 | 80.6 |
| 16 | KC | MAHOMES | 102.9 | 2.4 | 0.7 | 2.4 | QB | 7 | 164 | 248 | 66.1 | 1800 | 7.3 | 257.1 | 49 | 17 | 5 | 17 | 70 | 77.7 | 102.9 |
| 17 | LAC | HERBERT | 94.5 | 2.6 | 1.1 | 4.0 | QB | 7 | 183 | 271 | 67.5 | 1913 | 7.1 | 273.3 | 60 | 18 | 8 | 28 | 121 | 63.1 | 94.5 |
| 18 | LAR | BYE | 109.3 | 3.0 | 0.3 | 1.9 | QB | 7 | 160 | 242 | 66.1 | 1866 | 7.7 | 266.6 | 88 | 21 | 2 | 13 | 69 | 66 | 109.3 |
| 19 | LV | BYE | 77.1 | 1.6 | 1.6 | 3.0 | QB | 7 | 133 | 202 | 65.8 | 1417 | 7 | 202.4 | 61 | 11 | 11 | 21 | 146 | 34 | 77.1 |
| 20 | MIA | TUA | 82.8 | 2.1 | 1.6 | 2.6 | QB | 7 | 139 | 205 | 67.8 | 1313 | 6.4 | 187.6 | 47 | 15 | 11 | 18 | 80 | 42.5 | 82.8 |
| 21 | MIN | WENTZ | 89.3 | 1.0 | 1.0 | 3.5 | QB | 4 | 95 | 142 | 66.9 | 1072 | 7.5 | 268 | 81 | 4 | 4 | 14 | 98 | 42.6 | 89.3 |
| 22 | NE | MAYE | 116.4 | 2.4 | 0.6 | 4.9 | QB | 7 | 152 | 202 | 75.2 | 1744 | 8.6 | 249.1 | 55 | 17 | 4 | 34 | 77 | 76.8 | 116.4 |
| 23 | NO | RATTLER | 88.4 | 0.1 | 0.3 | 0.4 | QB | 7 | 159 | 235 | 67.7 | 1450 | 6.2 | 207.1 | 87 | 1 | 2 | 3 | 85 | 55.7 | 88.4 |
| 24 | NYG | DART | 89.3 | 1.7 | 0.5 | 3.2 | QB | 6 | 71 | 118 | 60.2 | 791 | 6.7 | 131.8 | 44 | 10 | 3 | 19 | 44 | 61.9 | 89.3 |
| 25 | NYJ | TAYLOR | 73.3 | 1.7 | 0.0 | 7.3 | QB | 3 | 43 | 69 | 62.3 | 379 | 5.5 | 126.3 | 35 | 5 | 0 | 22 | 51 | 36.5 | 73.3 |
| 26 | PHI | HURTS | 108.9 | 2.1 | 0.1 | 3.6 | QB | 7 | 136 | 195 | 69.7 | 1498 | 7.7 | 214 | 79 | 15 | 1 | 25 | 107 | 67.3 | 108.9 |
| 27 | PIT | RODGERS | 105 | 2.8 | 0.8 | 2.5 | QB | 6 | 118 | 172 | 68.6 | 1270 | 7.4 | 211.7 | 80 | 17 | 5 | 15 | 64 | 55 | 105 |
| 28 | SAN | JONES | 89.8 | 2.0 | 1.0 | 3.2 | QB | 5 | 130 | 194 | 67 | 1404 | 7.2 | 280.8 | 56 | 10 | 5 | 16 | 76 | 55.2 | 89.8 |
| 29 | SEA | BYE | 109.2 | 2.3 | 0.7 | 1.3 | QB | 7 | 131 | 192 | 68.2 | 1754 | 9.1 | 250.6 | 61 | 16 | 5 | 9 | 58 | 72.5 | 109.2 |
| 30 | TB | MAYFIELD | 99.8 | 1.9 | 0.3 | 2.4 | QB | 7 | 157 | 245 | 64.1 | 1767 | 7.2 | 252.4 | 77 | 13 | 2 | 17 | 92 | 63.5 | 99.8 |
| 31 | TEN | WARD | 70.9 | 0.7 | 0.9 | 5.4 | QB | 7 | 136 | 236 | 57.6 | 1356 | 5.7 | 193.7 | 47 | 5 | 6 | 38 | 237 | 23.9 | 70.9 |
| 32 | WSH | MARIOTA | 85.8 | 1.3 | 1.3 | 2.3 | QB | 3 | 35 | 58 | 60.3 | 426 | 7.3 | 142 | 56 | 4 | 4 | 7 | 26 | 59.2 | 85.8 |